Cambridge Healthtech Institute’s 7th Annual

Modulating the Tumour Microenvironment

Understanding the Mechanisms and Overcoming Immune Suppression

20-21 June 2023


Despite the amazing results from emerging immunotherapies such as immune checkpoint blockade and chimeric antigen receptor T cells (CAR Ts), not all cancer patients have benefitted from these innovative treatments yet because of innate and adaptive resistance. Further investigations into the tumour microenvironment are needed to better understand the mechanisms and develop means to overcome the immunosuppressive TME, thereby improving the safety and efficacy of novel immunotherapies. The Modulating the Tumour Microenvironment conference hopes to bring together leaders in the field to discuss advances in the understanding of and strategies to modulate the tumour microenvironment.


Coverage will include, but is not limited to:


  • Overcoming Resistance and Promoting Immune Activation in the TME
    • Role of tertiary and secondary lymphoid organs
    • Overcoming T cell exhaustion in the tumour
  • Immunoregulatory Cells and Their Immunostimulatory/Immunosuppressive Mechanisms
    • B cells
    • NK cells
    • Gamma delta T cells
    • Tumour-associated macrophages
    • MDSCs
    • Neutrophils
    • Fibroblasts
    • DC expansion/targeting
  • Extracellular Proteins, Cytokines and Signaling Molecules to Reprogram the TME
  • Addressing and Overcoming Solid Tumour Environments
  • Improving the Efficacy in Preclinical Models to Uncover Mechanisms and Predict Outcomes
    • Mechanistic modeling and 3D imaging for bench-to-bedside translation
    • Models for studying the TME


The deadline for priority consideration is 2 December 2022.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Mimi Langley

Senior Conference Director

Cambridge Healthtech Institute

Phone: +1 781 972 5439



For partnering and sponsorship information, please contact:

Rod Eymael

Manager, Business Development

Cambridge Healthtech Institute

Phone: +1 781-247-6286


Submit a Speaker Proposal